| 6492-2369 | 25-09-2021 | 14:00 | Orange Lions Academy Mannen U22 1 | BC APOLLO Amsterdam Mannen U22 1 | Sporthallen Zuid | 66 - 99 |
| 6492-2516 | 09-10-2021 | 15:00 | Heroes Den Bosch Mannen U22 1 | Orange Lions Academy Mannen U22 1 | De Schutskamp | 57 - 70 |
| 6492-2403 | 15-10-2021 | 20:00 | Orange Lions Academy Mannen U22 1 | BC Triple Threat Mannen U22 1 | Sporthallen Zuid | 69 - 52 |
| 6492-2504 | 19-10-2021 | 20:00 | Basketbal Academie Limburg Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Boshoven | 61 - 56 |
| 6492-2515 | 24-10-2021 | 15:00 | Donar Groningen Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Willem-Alexander Sportcentrum | 79 - 68 |
| 6492-2334 | 29-10-2021 | 20:00 | Orange Lions Academy Mannen U22 1 | Zorg en Zekerheid Leiden Mannen U22 1 | Sporthallen Zuid | 69 - 80 |
| 6492-2356 | 02-11-2021 | 19:00 | Orange Lions Academy Mannen U22 1 | Amstel State Mannen U22 1 | Sporthallen Zuid | 76 - 64 |
| 6492-2514 | 06-11-2021 | 19:00 | UBALL Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Sportcentrum Oudenrijn | 68 - 91 |
| 6492-2320 | 12-11-2021 | 19:30 | Orange Lions Academy Mannen U22 1 | Rotterdam Basketbal Mannen U22 1 | Sporthallen Zuid | 67 - 71 |
| 6492-2513 | 21-11-2021 | 19:00 | United Academy Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Sportcentrum De Schaapskooi | 78 - 61 |
| 6492-2446 | 25-11-2021 | 18:30 | Orange Lions Academy Mannen U22 1 | Landstede Hammers Mannen U22 1 | Sporthallen Zuid | 63 - 68 |
| 6492-2510 | 28-01-2022 | 20:45 | Amstel State Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Calandhal Hal 2 | 36 - 65 |
| 6492-2509 | 13-02-2022 | 16:30 | BC Triple Threat Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Spaarnehal | 40 - 60 |
| 6492-2431 | 04-03-2022 | 19:30 | Orange Lions Academy Mannen U22 1 | UBALL Mannen U22 1 | Sporthallen Zuid | 113 - 102 |
| 6492-2507 | 11-03-2022 | 21:00 | Rotterdam Basketbal Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Alexanderhal | 75 - 57 |
| 6492-2480 | 18-03-2022 | 19:30 | Orange Lions Academy Mannen U22 1 | United Academy Mannen U22 1 | Sporthallen Zuid | 48 - 67 |
| 6492-4048 | 27-03-2022 | 16:30 | D.B.V. Rowic Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Sportboulevard | 32 - 112 |
| 6492-2280 | 01-04-2022 | 19:30 | Orange Lions Academy Mannen U22 1 | Almere Pioneers Mannen U22 1 | Sporthallen Zuid | 100 - 37 |
| 6492-4035 | 26-04-2022 | 20:00 | Orange Lions Academy Mannen U22 1 | D.B.V. Rowic Mannen U22 1 | Sporthallen Zuid | 119 - 27 |
| 6492-2505 | 04-05-2022 | 14:00 | Landstede Hammers Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Topsporthal Centre Court | 47 - 87 |
| 6492-2511 | 08-05-2022 | 16:00 | BC APOLLO Amsterdam Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Apollohal | 74 - 62 |
| 6492-2512 | 21-05-2022 | 15:00 | Almere Pioneers Mannen U22 1 | Orange Lions Academy Mannen U22 1 | Almere Poort | 53 - 98 |